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2017, Development and Psychopathology
Although behavioral and experimental studies have shown links between victimization and antisocial behavior, the neural correlates explaining this link are relatively unknown. In the current study, we recruited adolescent girls from a longitudinal study that tracked youths' reports of peer victimization experiences annually from the 2 nd through 8 th grades. Based on these reports, 46 adolescents were recruited: 25 chronically victimized and 21 non-victimized. During an fMRI scan, participants completed a risk-taking task. Chronic peer victimization was associated with greater risk-taking behavior during the task and higher levels of self-reported antisocial behavior in everyday life. At the neural level, chronically victimized girls showed greater activation in regions involved in affective sensitivity, social cognition, and cognitive control, which significantly mediated victimization group differences in self-reported antisocial behavior.
Molecular Psychiatry, 2018
Chronic peer victimization has long-term impacts on mental health; however, the biological mediators of this adverse relationship are unknown. We sought to determine whether adolescent brain development is involved in mediating the effect of peer victimization on psychopathology. We included participants (n=682) from the longitudinal IMAGEN study with both peer victimization and neuroimaging data. Latent profile analysis identified groups of adolescents with different experiential patterns of victimization. We then associated the victimization trajectories and brain volume changes with depression, generalized anxiety, and hyperactivity symptoms at age 19. Repeated measures ANOVA revealed time-by-victimization interactions on left putamen volume (F=4.38, p=0.037). Changes in left putamen volume were negatively associated with generalized anxiety (t=-2.32, p=0.020). Notably, peer victimization was indirectly associated with generalized anxiety via decreases in putamen volume (95%CI=0.004 to 0.109). This was also true for the left caudate (95%CI=0.002 to 0.099). These data suggest that the experience of chronic peer victimization during adolescence might induce psychopathology-relevant deviations from normative brain development. Early peer victimization interventions could prevent such pathological changes.
Frontiers in Behavioral Neuroscience, 2019
Peer victimization (or bullying) is a known risk factor for depression, especially among youth. However, the mechanisms connecting victimization experience to depression symptoms remains unknown. As depression is known to be associated with neural blunting to monetary rewards, aberrant responsiveness to social rewards may be a key deficit connecting socially stressful experiences with later depression. We, therefore, sought to determine whether adolescents' experiences with social stress would be related to their current response to social rewards over less socially relevant monetary rewards. Neural responses to monetary and social rewards were measured using event-related potentials (ERPs) to peer acceptance and rejection feedback (Island Getaway task) and to monetary reward and loss feedback (Doors task) in a sample of 56 late adolescents/emerging young adults followed longitudinally since preschool. In the Island Getaway task, participants voted whether to "keep" or "kick out" each co-player, providing an index of prosocial behavior, and then received feedback about how each player voted for the participant. Analyses tested whether early and recent peer victimization was related to response to rewards (peer acceptance or monetary gains), residualized for response to losses (peer rejection or monetary losses) using the reward positivity (RewP) component. Findings indicated that both experiencing greater early and greater recent peer victimization were significantly associated with participants casting fewer votes to keep other adolescents ("Keep" votes) and that greater early peer victimization was associated with reduced neural response to peer acceptance. Early and recent peer victimization were significantly more associated with neural response to social than monetary rewards. Together, these findings suggest that socially injurious experiences such as peer victimization, especially those occurring early in childhood, relate to two distinct but important findings: that early victimization is associated with later reduced response to peer acceptance, and is associated with later tendency to reject
Social cognitive and affective neuroscience, 2017
Maltreatment is associated with increased risk of a range of psychiatric disorders, many of which are characterized by altered risk-taking propensity. Currently, little is known about the neural correlates of risk-taking in children exposed to maltreatment, nor whether their risk-taking is atypically modulated by peer influence. Seventy-five 10-14 year-old children (maltreated (MT) group: N = 41; non-maltreated Group (NMT): N = 34) performed a Balloon Analogue Risk Task (BART), under three different peer influence conditions: while alone; while being observed by a peer; while being encouraged by a peer to take risks. The MT group engaged in less risk-taking irrespective of peer influence. There was no differential effect of peer influence on risk-taking behaviour across groups. At the neural level the right anterior insula (rAI) exhibited altered risk-sensitivity across conditions in the MT group. Across groups and conditions, rAI risk-sensitivity was negatively associated with risk...
Neurobiological and behavioral findings suggest that the development of delinquent behavior is associated with atypical social-affective processing. However, to date, no study has examined neural processes associated with social interactions in severely antisocial adolescents. In this study we investigated the behavioral and neural processes underlying social interactions of juvenile delinquents and a matched control group. Participants played the mini-Ultimatum Game as a responder while in the MRI scanner. Participants rejected unfair offers significantly less when the other player had 'no alternative' compared with a 'fair' alternative, suggesting that they took the intentions of the other player into account. However, this effect was reduced in the juvenile delinquents. The neuroimaging results revealed that juvenile delinquents showed less activation in the temporal parietal junction (TPJ) and inferior frontal gyrus (IFG). However, the groups showed similar activation levels in the dorsal anterior cingulate cortex (dACC) and the right anterior insula (AI) when norms were violated. These results indicate that juvenile delinquents with severe antisocial behavior process norm violations adequately, but may have difficulties with attending spontaneously to relevant features of the social context during interactions.
Social Neuroscience, 2010
Relational aggression describes a type of aggression that aims to hurt others through relationships and includes behaviors such as gossip and ostracism. This type of aggression is very common among adolescent girls; and in its more intense forms has been linked with poor psychosocial outcomes, including depression and suicide. In the present study we investigated whether individual differences in sensitivity to relational aggression among adolescent girls predicted recruitment of neural networks associated with executive function and cognitive control. Neural response was measured using functional magnetic resonance imaging (fMRI) during an affect recognition task that included unfamiliar peer faces. We found that relatively fewer reports of being victimized by relational aggression was associated increased recruitment of bilateral dorsolateral prefrontal cortices as well as anterior and posterior cingulate cortices in response to the affect recognition task, as well as with greater competence on behavioral measures of executive function. Our results suggest that girls who are able to recruit specific frontal networks to improve cognitive and executive control are relatively less sensitive to relational aggression.
Development and Psychopathology, 2004
Using a short-term longitudinal design, internalizing and externalizing emotions were examined as risk factors for being victimized by peers in early childhood. Regulation, aggression, and withdrawal were also tested as mediators. We found that anger, mediated by aggression and regulation, positively predicted being victimized, although the way in which anger related to victimization risk varied for boys and girls and across time. These findings were robust, particularly for girls, attesting to the importance of externalizing variables as risk factors for young children's victimization. Support for internalizing variables as risk factors for being victimized was weak. The implications of the findings for developmental models connecting symptomatology and victimization are discussed. The authors thank all of the students, children, parents, and teachers who participated in this research. RichardA. Fabes
Developmental Psychology, 2009
This study examined whether exposure to relational victimization was associated with children's thoughts, emotions, and behavior in an unfamiliar, challenging peer context. Children (110 girls, 96 boys; M age = 10.13 years, SD = 1.16) reported on their exposure to relational victimization by peers. Following a challenging interaction with an unfamiliar peer, children reported on their beliefs about their interaction partners and their social goals (i.e., focus on getting to know their partner versus impressing their partner) during the interaction. Coders rated children's emotion and behavior regulation and the quality of the dyadic context. Results from hierarchical linear modeling analyses revealed that relational victimization predicted maladaptive social-cognitive processes (i.e., more negative peer beliefs and a heightened performance goal orientation) and heightened emotion and behavior dysregulation. Several of these effects were particularly salient in the context of a conflictual dyadic interaction. This research provides insight into impairments associated with relational victimization that may contribute to the emergence and/or perpetuation of peer difficulties. Relational victimization is defined as exposure to behaviors aimed at damaging relationships or one's social reputation, such as exclusion, manipulation, and rumor-spreading (Crick & Grotpeter, 1996). Research links relational victimization within the broader peer group (classmates or schoolmates) and within more intimate relationships (friendships) to emotional,
Developmental Cognitive Neuroscience, 2021
The adaptive calibration model suggests exposure to highly stressful or highly supportive early environments sensitizes the brain to later environmental input. We examined whether family and peer experiences predict neural sensitivity to social cues in 85 adolescent girls who completed a social feedback task during a functional brain scan and an interview assessing adversity. Whole-brain functional connectivity (FC) analyses revealed curvilinear associations between social experiences and FC between the ventral striatum and regions involved in emotion valuation, social cognition, and salience detection (e.g., insula, MPFC, dACC, dlPFC) during social reward processing, such that stronger FC was found at both very high and very low levels of adversity. Moreover, exposure to adversity predicted stronger FC between the amygdala and regions involved in salience detection, social cognition, and emotional memory (e.g., sgACC, precuneus, lingual gyrus, parahippocampal gyrus) during social threat processing. Analyses also revealed some evidence for blunted FC (VS-PCC for reward; amygdala-parahippocampal gyrus for threat) at very high and low levels of adversity. Overall, results suggest social experiences may play a critical role in shaping neural sensitivity to social feedback during adolescence. Future work will need to elucidate the implications of these patterns of neural function for the development of psychopathology.
Developmental Science, 2013
During adolescence, concerns about peer rejection and acceptance become increasingly common. Adolescents regularly experience peer rejection firsthand and witness these behaviors among their peers. In the current study, neuroimaging techniques were employed to conduct a preliminary investigation of the affective and cognitive processes involved in witnessing peer acceptance and rejectionspecifically when these witnessed events occur in the immediate aftermath of a firsthand experience with rejection. During an fMRI scan, 23 adolescents underwent a simulated experience of firsthand peer rejection. Then, immediately following this experience they watched as another adolescent was ostensibly first accepted and then rejected. Findings indicated that in the immediate aftermath of being rejected by peers, adolescents displayed neural activity consistent with distress when they saw another peer being accepted, and neural activity consistent with emotion regulation and mentalizing (e.g. perspective-taking) processes when they saw another peer being rejected. Furthermore, individuals displaying a heightened sensitivity to firsthand rejection were more likely to show neural activity consistent with distress when observing a peer being accepted. Findings are discussed in terms of how witnessing others being accepted or rejected relates to adolescents' interpretations of both firsthand and observed experiences with peers. In addition, the potential impact that witnessed events might have on the broader perpetuation of bullying at this age is also considered.
2012
Abstract Adolescence is a period of intensified emotions and an increase in motivated behaviors and passions. Evidence from developmental neuroscience suggests that this heightened emotionality occurs, in part, due to a peak in functional reactivity to rewarding stimuli, which renders adolescents more oriented towards reward-seeking behaviors. Most prior work has focused on how reward sensitivity may create vulnerabilities, leading to increases in risk taking.
NeuroImage, 2013
Social exclusion and risk-taking are both common experiences of concern in adolescence, yet little is known about how the two may be related at behavioral or neural levels.
Brain and cognition, 2010
Journal of Consulting and Clinical Psychology, 2009
Peer victimization experiences represent developmentally salient stressors among adolescents and are associated with the development of internalizing symptoms. However, the mechanisms linking peer victimization to adolescent psychopathology remain inadequately understood. This study examined emotion dysregulation as a mechanism linking peer stress to changes in internalizing symptoms among adolescents in a longitudinal design. Peer victimization was assessed in a large (N = 1,065) racially diverse (86.6% non-White) sample of adolescents ages 11 to 14 using the Revised Peer Experiences Questionnaire. Emotion dysregulation and symptoms of depression and anxiety were also assessed. Structural equation modeling was used to create a latent construct of emotion dysregulation from measures of discrete emotion processes and of peer victimization and internalizing symptoms. Peer victimization was associated with increased emotion dysregulation over a 4-month period. Increases in emotion dysregulation mediated the relationship between relational and reputational, but not overt, victimization and changes in internalizing symptoms over a 7-month period. Evidence for a reciprocal relationship between internalizing symptoms and relational victimization was found, but emotion dysregulation did not mediate this relationship. The implications for preventive interventions are discussed.
The Journal of Pediatrics
Objective To assess the relation between early social behavioral tendencies and the risk of violent victimization in late adolescence. Study design We analyzed 5 waves of data from the Zurich Project on the Social Development from Childhood into Adulthood (z-proso), a longitudinal sample of Swiss first graders (N = 1138). Early social behavioral tendencies were measured at age 7 years and included internalizing problems, externalizing behavior, prosocial behavior, negative peer relations, competent problem solving, dominance, and sensation seeking. Path analyses were conducted of the association between these tendencies and violent victimization at age 17 years, and mediation through intermediate victimization at ages 11, 13, and 15 years was examined. Results Several childhood social behavioral tendencies predicted victimization 10 years later. Though this was the case for both sexes, the number and type of significant risk factors differed. For male children, sensation seeking, externalizing behavior, high prosociality, and negative peer relations at age 7 years increased later victimization, whereas for female children, dominance and externalizing behavior were predictive. In addition, results showed that the relation between early risk factors and age 17 years victimization was mediated by intermediate victimization, showing that differences in victimization risk in early adolescence are carried forward into late adolescence. Conclusions Childhood social behavioral tendencies predict victimization 10 years later. Incorporating this finding into early prevention programs could reduce victimization over the life course.
PloS one, 2021
Relational bullying in schools is one of the most frequent forms of violence and can have severe negative health impact, e.g. depression. Social exclusion is the most prominent form of relational bullying that can be operationalized experimentally. The present study used MR-based perfusion imaging (pCASL) to investigate the neural signatures of social exclusion and its relationship with individually different extent of previous bullying experience. Twenty-four teenagers reporting bullying experience at different extent were scanned during a virtual ball-tossing (Cyberball game). Our findings showed that social exclusion (relative to social inclusion) activated frontal brain areas: sub- and perigenual anterior cingulate cortex (sg/pgACC), left inferior frontal cortex (IFG), and dorsolateral prefrontal cortex. Positive relationship between exclusion-specific signal increase and individually different extents of prior bullying experience was for the first time observed in left IFG and ...
School Psychology Quarterly, 2014
Prior research has demonstrated that victims of peer victimization show reduced psychological adjustment, social adjustment, and physical well-being compared with nonvictims. However, little research has addressed whether this maladjustment continues over the long term. This study examined adjustment in 72 high school students who had participated in a peer-nomination procedure assessing peer victimization when in elementary school (5 to 8 years earlier). Thirty-five high school students who had been peer nominated as overtly and/or relationally peer victimized were compared with 37 peers who were not nominated as victimized in elementary school. High school students completed self-report measures of psychological adjustment, social adjustment, physical well-being, and current overt and relational victimization. In addition, a retrospective self-report measure of peer victimization in elementary school was administered. Results revealed that, although current self-reported peer victimization was negatively related to adjustment, elementary-school peer-nomination measures of victimization were unrelated to high-school adjustment. Further, current self-reports of remembered victimization in elementary school were associated with lowered adjustment. These results indicate that current and past perceived peer victimization is negatively related to adjustment, but past experience of peer-identified victimization has a more complex relation to current adjustment.
Development and psychopathology, 2014
The link between the experience of peer victimization (PV) and future psychological maladjustment has been consistently documented; however, little is known about intermediary cognitive processes that underlie this relation or how these processes vary across childhood. The present study examined the prospective relations between physical and relational PV and the development of negative and positive automatic thoughts and self-cognitions. Self-reports of cognitions and peer nomination measures of victimization were obtained from 1,242 children and young adolescents (Grades 3 through 6) in a two-wave longitudinal study. The results revealed that PV predicted significant increases in negative views of the self, world, and future and decreases in self-perceived competence for girls under 11 years of age, with the effect being stronger for younger girls. PV was not significantly associated with changes in positive or negative self-cognitions for older girls or for boys of any age. These...
Development and Psychopathology, 2019
Difficulties with emotion regulation can take many forms, including increased sensitivity to emotional cues and habitual use of maladaptive cognitive or behavioral regulation strategies. Despite extensive research on emotion regulation and youth adjustment, few studies integrate multiple measures of emotion regulation. The present study evaluated the underlying structure of emotion regulation processes in adolescence using both task- and survey-based measures and determined whether differences in these emotion regulation latent factors mediated the association between peer victimization and internalizing psychopathology. Adolescents aged 16–17 years (n = 287; 55% female; 42% White) recruited in three urban centers in the United States completed baseline and follow-up assessments 4 months apart. Three models of emotion regulation were evaluated with confirmatory factor analysis. A three-factor model fit the data best, including cognitive regulation, behavioral regulation, and emotion...
Recent structural and functional imaging studies have provided evidence for continued development of brain regions involved in social cognition during adolescence. In this paper, we review this rapidly expanding area of neuroscience and describe models of neurocognitive development that have emerged recently. One implication of these models is that neural development underlies commonly observed adolescent phenomena such as susceptibility to peer influence and sensitivity to peer rejection. Experimental behavioural evidence of rejection sensitivity in adolescence is currently sparse. Here, we describe a study that directly compared the affective consequences of an experimental ostracism manipulation (Cyberball) in female adolescents and adults. The ostracism condition led to significantly greater affective consequences in the adolescents compared with adults. This suggests that the ability to regulate distress resulting from ostracism continues to develop between adolescence and adulthood. The results are discussed in the context of models of neurocognitive development.
Journal of Research on Adolescence, 2007
Peer victimization has been linked concurrently and over time with multiple adjustment problems. However, the reasons for this multi-finality in victimization are not well understood. The current study examines socialcognitive processes (hostile attributions, social perspective awareness, and interpersonal skills) as mediators of the relations between subtypes of peer victimization (relational, physical) and depression and anxiety, social withdrawal, and physical aggression in early adolescence. The overall pattern of associations among subtypes of victimization, social-cognitive processes, and adjustment converged with expectations that victimization biases adolescents' cognitions about peers in conflict situations and skills relating to peers. In turn, these cognitions and skills differentially compromised their ability to regulate diverse emotions or limit reticent behaviors in response to peer threats. Modest gender differences in these associations were found. Research has identified two primary forms of peer victimization. Relational victimization damages adolescents' relationship ties through the manipulation of social status and friendships. Physical victimization threatens adolescents' feelings of safety and power among peers through physical assaults and verbal threats of harm (Crick & Grotpeter, 1996). While
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